An unusual presentation of giant cell tumour (osteoclastoma).
نویسندگان
چکیده
The number of well-documented true giant cell tumours arising in any of the craniofacial bones is small, but they do exist. A 19 year old female, Ms. KS, presented with complain of progressive enlargement of facial bones especially jaw bones, then orbit symmetrically since the age of 7. There was bilateral gross enlargement of mandible, maxilla, orbital walls, causing displacement of eye medially and upwards. The visual acuity of both eyes were 6/36 and 6/18 with best correction. Extra ocular movements were restricted because of bony growth and conjunctiva over inferior fornix were keratinized due to exposure. Fine needle aspiration (FNAC) from the side of bony growth showed plenty of osteoclasts with multinucleated giant cells. The level of serum alkaline phosphatase were highly increased. She underwent orbitotomy and a part of tissue was sent for biopsy which revealed multiples of mononucleargiant cells and tumour cells.
منابع مشابه
Giant cell tumour (osteoclastoma) of the pancreas--an epithelial tumour probably of pancreatic acinar origin.
A case of giant cell tumour of the pancreas has been studied. The light microscopical appearance of the tumour is indistinguishable from osteoclastoma of bone. Electron microscopy of the tumour shows many typical desmosomes between stromal cells. This is strong evidence of its epithelial nature. The cytoplasm of both the osteoclast-like giant cells and stromal cells contain abundant rough endop...
متن کاملOsteoclastoma of the orbit. Case report.
TUMOURS characterized by the presence of giant cells are not uncommonly seen in sections from orbital masses. The histologic appearance of osteoclastoma as first described by N6laton (1860) is of tumours consisting essentially of spindle cells, round cells, and multinucleated giant cells with an abundance of nuclei. It is a rare tumour, which until recently had not been differentiated from othe...
متن کاملAggressive Osteoclastoma of Sphenoid Sinus: A Rare Surgical Case Report
The giant cell tumor (GCT) or osteoclastoma is considered to be a locally aggressive benign tumor. The GCTs of the cranium represent only 1% of all GCTs and preferentially affect the sphenoid and temporal bones. We report a case of an 18-year-old male who presented with headache and diplopia. Radiological investigation shows a destructive midline mass involving the body of the sphenoid. The tum...
متن کاملA remote metastatic giant cell tumour to the skull
This case discusses an unusual presentation of remote metastatic giant cell tumour presenting as a seizure.
متن کاملInfected Osteoclastoma of the Knee: An Unusual Presentation
Introduction. Giant cell tumor is a benign or locally aggressive tumor of uncertain origin that appears in mature bone, most commonly in the distal femur, proximal tibia which characteristically extends right up to the subarticular bone plate. Case Report. We report here a 35-year-old female presenting with swelling of the left knee. On examination, the swelling was solitary, about 20 × 15 cm i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Kathmandu University medical journal
دوره 1 3 شماره
صفحات -
تاریخ انتشار 2003